Viagra (Sildenafil Citrate) Reviews and Drug Information

Archive for August, 2012

Viagra Wonder Is Still On!

Posted by Viagra Ed On August - 24 - 2012 ADD COMMENTS Subscribe here

The wonder of viagra will never cease! There was the Peruvian viagra, viagra ice cream, viagra to cure jet lag and now the most recent – Viagra Oyster. It’s funny but true that Viagra has remarkably maintained its popularity in spite of being launched nearly a decade ago and facing controversies now and then. Further, many competitors have come and gone but the Viagra magic is still on. In regard to impotency Viagra is the father of all and has influenced the entire world in curing impotency.

No drug has ever been as popular as viagra. The very word Viagra pills online has become synonymous of impotency although there are many other drugs available which even work and last longer than viagra. Though this drug is meant for the use of males only, it is one of the most searched word on the internet and the most spoken about medicine. It has also become the pun of many jokes and thereby helps in spreading smiles and happiness.

Viagra is being popularized again and again through the use of its name whenever a new discovery is made via any drug, drink or food. The use of words such as the “new viagra food,” “new viagra drink,” “new viagra chocolate” etc will never end. Though, the use of Viagra word has greatly elevated the popularity of viagra as an important drug by labeling each and every stuff found to be having the potential of curing impotency, it can also bring it down and tarnish the real image of viagra if the so called drugs or drinks don’t live up their name. Further, it breaches the patent right.

Viagra though is potent of giving satisfying results; it too has limits which should never be overlooked. Viagra should always be taken in consultation with your doctor. Viagra which actually is sildenafil should not be taken along with nitrates as it can even cause deaths. Taking of nitroglycerin patches, nitroglycerin ointment, pills or nitroglycerin ointment or isosorbide pills along with viagra causes the blood sugar to drop so low that it may lead to death.

Therefore, when new things come in the market like the recent Viagra oyster you should not rush to it. It is important to check out the safety measures first. For many people the viagra oyster may be a nice delicacy which can be food as well as a medicine but do you know the side effects? As the oysters were fed on the crushed Viagra and some minerals they are not the same as the natural oyster. Therefore, whenever any anti-impotency drugs or local remedies are discovered do not rush to it until and unless proper research or studies are done on the subject.

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Exactly What Is Viagra

Posted by Viagra Ed On August - 23 - 2012 ADD COMMENTS Subscribe here

Exactly what Is Viagra

What’s Viagra?Viagra is an anti-impotence drug with an energetic ingredient sildenafile citrate for remedy of male impotence. Sildenafile citrate relaxes the muscular tissues and will raise the blood circulation to distinct places of the whole body. The usage of Viagra raises the capacity to know and maintain erection on getting sexually stimulated. Adult males taking Viagra have reported an amplified intercourse push, accelerated stamina, and more quickly recharge. Viagra functions together with sexual stimulation to allow receive most sexual satisfaction. Nonetheless, Viagra does not assure security from discovering sexually transmitted well being circumstances, collectively with HIV and Hepatitis.How Viagra will work? Viagra permits countless males with ED to respond to sexual stimulation.

When a guy is sexually aroused, the arteries in the penis loosen up and widen, permitting for even more blood to circulate into the penis. Because the arteries in the penis develop and harden, the veins that typically carry blood away from the penis establish into compressed, limiting the blood move out of the penis. With additional blood flowing in and much less flowing out, the penis enlarges, top to an erection. It is truly to become well-liked that Viagra should not be a hormone or aphrodisiac, it seriously performs exclusively when a guy is sexually stimulated.Viagra DosageViagra is obtainable in the kind of tablet and is meant to be taken orally. Ideally it is to become taken virtually an hour previously than the sexual physical exercise. Even so, Viagra might be taken anytime from four hrs to thirty minutes prior to than sexual activity.

It usually requires thirty – forty five minutes for displaying Viagra’s impression and this impact lasts for nearly four hours. In case you receive Viagra right following an extreme-fats meal (corresponding to fish & chips, cheeseburger or French fries), it could consider considerably for a longer period to start off functioning. Viagra ought to not be used extra than as soon as a day until eventually prescribed by your doctor.

Warnings/Precautions

It’s continually advisable to seek out the recommendation of physician prior to than starting the consumption of Viagra. In scenario you might have the historical past of an coronary heart attack, stroke, or lifestyle-threatening irregular heartbeats inside the last 6 months or have coronary coronary heart failure earlier coronary artery sickness angina high or lower blood stress liver challenges kidney concerns blood complications, like sickle cell anemia or leukemia a bleeding dysfunction belly ulcer retinitis pigmentosa (an inherited circumstance of the attention) bodily deformity from the penis equivalent to Peyronie’s disorder or an issue that could lead to extended and distressing erections, resembling a tumor from the bone marrow, sickle cell anemia, or leukemia or you just take some other medication that contains nitrates your blood emotional stress could all of a sudden drop to an unsafe level and can risk your life.

All these clinical conditions and in addition allergy to sildenafile or any of its components can result in disastrous benefits. So it’s all the time highly recommended to look for the information of your medical professional for adjusting the dosages just after monitoring the treatments detailed previously mentioned.Viagra is not authorized or endorsed to become employed in women. Due to this truth, ladies need to not just take Viagra beneath any circumstances. It moreover not advantageous for males older than 65 a long time apart from they tolerate it in compact doses for these who are delicate to the results of Viagra.Missed DoseViagra may be used as and when wanted and there’s no concept of missed dosage.Doable Side Effects of ViagraEvery medicine has some or the opposite facet result and so does Viagra. It is dependent upon personal to special human being and is usually mild to moderate and do not very last much more time than a few of hrs. Principally these undesirable side results are evident with higher intakes of Viagra.

The commonest unintended effects of Viagra are headache, nausea, flushing of the confront, and upset stomach. In addition there will be some momentary adjustments in coloration vision (resembling bother telling the big difference concerning blue and inexperienced objects or obtaining a blue coloration tinge to them), eyes modifying into delicate to gentle, or blurred eyesight.But when you turn out to become dizzy or nauseated, or have ache, numbness, or tingling in your chest, arms, neck, or jaw all through sexual activity, cease and contact your doctor proper away. You could maybe be getting a severe aspect impact of Viagra, or in scenario you have sudden imaginative and prescient damage or have any of these indicators of allergic reactions like hives issues respiration inflammation of your face, lips, tongue, or throat search emergency professional medical enable without delay. It’s generally highly recommended to cease using Viagra and simply call your medical doctor instantaneously when you have any of these imperative problems like – chest ache or weighty feeling, discomfort spreading to the arm or shoulder, nausea, sweating, common sick feeling irregular heartbeat swelling in your arms, ankles, or ft shortness of breath and imaginative and prescient variations.In uncommon circumstances, males have described an erection that lasts numerous hours. But if this is the situation then you require to identify a doctor without delay if an erection lasts far more than four hours. If not handled appropriate away, everlasting harm to your penis could arise. Heart assault, stroke, irregular heartbeats, and dying have been noted hardly ever before in males taking Viagra. Most, but not all, of all those males had coronary heart matters just before taking this medicine. It’s not doable to determine no matter if these occasions had been instantly connected to Viagra.The www.indianviagra.org online websit providing Viagra for sale can be readily accessed on the online world.

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Oral Phosphodiesterase

Posted by Viagra Ed On August - 22 - 2012 ADD COMMENTS Subscribe here

Oral Phosphodiesterase

  1. Inhibitors PDE­5
  2. Pharmacokinetics and pharmacodynamics
  3. Side effects
  4. Safety
  5. Comparison

Phosphodiesterase, as mentioned in the previous  section, is paramount to the breakdown of cGMP  in the SMC. This enzyme is found in several dif­ ferent tissues throughout the body and has been  categorized into 11 families. The family that is  found in corpora cavernosum tissue as well as  smooth muscle and vascular smooth muscle is  PDE­5. As the role of PDE­5 was elucidated in  the 1980s, drugs were targeted to inhibit this  enzyme and increase the NO in SMCs. A result  of this was an unexpected increase in NO in  penile tissue and improvement in erectile  function. PDE­5 inhibitors were first marketed in 1998  with the dawn of sildenafil (Viagra®). This was  followed closely in 2003 with vardenafil  (Levitra®) and tadalafil (Cialis®). As the market  for these drugs has increased, it has been impor­ tant to identify the safety, efficacy, and limita­ tions of these drugs. When choosing a PDE­5  inhibitor for a patient, it is important to know  the onset of action, efficacy, and duration.  Studies usually will define the maximal plasma  concentration (Cmax ), time to reach this plasma  concentration (Tmax ), and the plasma half­life  (t ½). How well these laboratory findings corre­ late to clinical findings is sometimes difficult to  determine and the measuring tool most com­ monly used to evaluate efficacy is the International Index of Erectile Function (IIEF)  domain score.

Viagra®

The most studied of these drugs is sildenafil  (Viagra®). In several placebo controlled, ran­ domized trials, this drug has been shown to  improve erectile function. The pivotal study for  sildenafil was published in 1998, which showed  a clinically and statistically significant improve­ ment in IIEF domain scores for men suffering  from ED for greater than 5 years. The onset  of action of sildenafil is approximately 20 min with a reported  t ½ of 3–5  h and duration of  action as long as 12 h. The important thing  about sildenafil is that it should not be taken  with a high­fat meal because this will decrease  the absorption of the medication. Female Viagra Australia

Levitra®

The FDA approved vardenafil (Levitra®) in  2003 after a study of 805 men with ED showed  a clinically and statistically significant improve­ ment in IIEF scores when compared to placebo. In this study, different doses were evaluated and  men were categorized into mild, moderate, and  severe ED. Approximately 40% of the moder­ ate and severe ED men had improvement with  the highest dose and over 79% of the mild ED  men had improvement. Vardenafil is  quickly absorbed with a Tmax  of 45 min and a  reported t ½ of 4–5 h. Onset of action has been  recorded as early as 10  min [17]. Just as in  sildenafil, it is recommended that high­fat meals  are avoided.

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