Viagra (Sildenafil Citrate) Reviews and Drug Information

Oral Phosphodiesterase

1. Inhibitors PDE­5
2. Pharmacokinetics and pharmacodynamics
3. Side effects
4. Safety
5. Comparison

Phosphodiesterase, as mentioned in the previous  section, is paramount to the breakdown of cGMP  in the SMC. This enzyme is found in several dif­ ferent tissues throughout the body and has been  categorized into 11 families. The family that is  found in corpora cavernosum tissue as well as  smooth muscle and vascular smooth muscle is  PDE­5. As the role of PDE­5 was elucidated in  the 1980s, drugs were targeted to inhibit this  enzyme and increase the NO in SMCs. A result  of this was an unexpected increase in NO in  penile tissue and improvement in erectile  function. PDE­5 inhibitors were first marketed in 1998  with the dawn of sildenafil (Viagra®). This was  followed closely in 2003 with vardenafil  (Levitra®) and tadalafil (Cialis®). As the market  for these drugs has increased, it has been impor­ tant to identify the safety, efficacy, and limita­ tions of these drugs. When choosing a PDE­5  inhibitor for a patient, it is important to know  the onset of action, efficacy, and duration.  Studies usually will define the maximal plasma  concentration (Cmax ), time to reach this plasma  concentration (Tmax ), and the plasma half­life  (t ½). How well these laboratory findings corre­ late to clinical findings is sometimes difficult to  determine and the measuring tool most com­ monly used to evaluate efficacy is the International Index of Erectile Function (IIEF)  domain score.

Viagra®

The most studied of these drugs is sildenafil  (Viagra®). In several placebo controlled, ran­ domized trials, this drug has been shown to  improve erectile function. The pivotal study for  sildenafil was published in 1998, which showed  a clinically and statistically significant improve­ ment in IIEF domain scores for men suffering  from ED for greater than 5 years. The onset  of action of sildenafil is approximately 20 min with a reported  t ½ of 3–5  h and duration of  action as long as 12 h. The important thing  about sildenafil is that it should not be taken  with a high­fat meal because this will decrease  the absorption of the medication. Female Viagra Australia

Levitra®

The FDA approved vardenafil (Levitra®) in  2003 after a study of 805 men with ED showed  a clinically and statistically significant improve­ ment in IIEF scores when compared to placebo. In this study, different doses were evaluated and  men were categorized into mild, moderate, and  severe ED. Approximately 40% of the moder­ ate and severe ED men had improvement with  the highest dose and over 79% of the mild ED  men had improvement. Vardenafil is  quickly absorbed with a Tmax  of 45 min and a  reported t ½ of 4–5 h. Onset of action has been  recorded as early as 10  min [17]. Just as in  sildenafil, it is recommended that high­fat meals  are avoided.

Viagra for women serve very much similar purpose as the male Viagra does for men, it increments the women’s libido for sex. Just like Viagra can be had in many forms, the same goes in case of Viagra for women as well. A bunch full of alternatives are available in the market in this regard including capsules, trans dermal patches, cream, et al. It would be reasonable to buy female Viagra in any of these forms if you are really desirous to overcome those mood swings and outperform your male counterpart on bed.

Why Viagra for women?

Since years, Viagra has only been identified as blue pills, used for the treatment of Erectile Dysfunction among men as if women would never have had any sex related issues. But in fact, women may also be compelled to face the problems of decreased sex desire due to many reasons and the decision to buy female Viagra could provide them deep routed respite from such afflictions. There could be many reasons for the sluggish sex desire that may include hormonal changes such as pre-menstrual or post pregnancy illness and physical, emotional or psychological turmoils. Besides these, stress and depression are also the big culprit to kill the women’s erotic senses. To overcome all these problems and help the women to play active part in a sex drive, Viagra for women truly holds the key.

How female Viagra works?

Women who buy Female Viagra undoubtedly are desirous of instant results and these viable medicines are just bang on target to fulfill such a desire. Most of the Viagra for women are effective herbal alternatives and increase blood flow thereby allowing clitoral engorgement to a great extent, just like a male Viagra works actively towards erecting the penis by increasing the blood flow. This in turn makes the female’s vagina to produce moisture in the form natural juices. Mostly available in the form of cream or gel that is applied to the clitoral region, Viagra for women hence enhances the size of the vagina and makes it highly sensitive to penetration by the hard and erected penis of their male partners.

Side-effects of Viagra for women

While you buy female Viagra, you can be rest assured of its efficacy in giving a significant twist to your aphrodisiac sexual urge. In the meantime, if you are worrying of its side-effects, then you need not to do so. Fortunately, unlike their other versions for men, Viagra for women are completely sanctified from the harmful side-effects and are more likely to bring about the desired results without causing any problem to your health. This is probably due to the reason that these Viagra drugs are mostly composed of natural and organic botanical constituents. Hence any possibility of perfume, preservative or any other such unnatural ingredient in their composition is discouraged thereby making them duly sanctified from side-effects.

A 47 years old, of Cincinnati uses Viagra regularly says that unlike men, Viagra in women can lead to a clear sense of where you are. “I felt like a tingling in the pelvic area,” he says. “I almost could increase blood flow. It was like there was an increase in sensitivity.

The woman gave to your doctor Viagra after a hysterectomy, which is almost impossible to orgasm. She said that Viagra has more than 70% of sexual function. The level of orgasm “is not exactly what I had before – not as full,” he says. “But it’s easier.”

Early studies of Viagra and women do not find work, but doctors say that the studies were not sufficiently selective, and even women with desire disorders, such as men who have such problems, can not be helped by Viagra.

As with men, Viagra is blood flow to the genitals in women. For women who have difficulty achieving orgasm, vaginal dryness or lack of feeling of excitement or engorgement, Viagra may help.

In a recent study of 200 postmenopausal women who had experienced either, and hysterectomy, all in some kind of sexual arousal disorder, half were given Viagra for woman and half received a placebo. The researchers found that 57% of women, Viagra reported improved sensation in the genital area, compared with 44% in the placebo group.

Although many researchers say sexual problems are more complicated in women than in men, and unlikely Viagra always work as well as for women than for men.

What are the Most Common Side Effects, and brings them all?

In addition to helping you have sex, Viagra often gives you headaches, a stuffy nose and a drain, his face beet red. But anyone who uses it seems to forget that a lot. In studies, only about 1% of the population declined because of side effects – exactly the same as those of a placebo.

A strange side effect is visual disturbances, including a blue-green tinge to vision, which is about 3% of the time. In studies, about half of the men, the Viagra experience at least one side, and the incidence is higher at higher doses. For men, the Viagra 100 mg in five trials, 23% had headaches, 17% a red face, and 12% had stomach pain. Side effects appear to be similar for women. Side effects tend to disappear with use, if a patient said he liked the Viagra gave him a headache because I knew that meant he was ready.

David Nail, 39, of West Hollywood, California, began with Viagra after a car accident has with spinal cord injury. He says sex is actually better than before his accident and experienced a strong orgasm. Initially, 50 mg of Viagra he bluish vision and a slight headache. Now rarely gets a headache, and the vision side effect has stopped

Review Summary

Lovegra is sometimes referred to as the female Viagra or the little pink pill. Interestingly, some vendors and distributors are marketing this formula for men as well. Men seeking a sexual aid should immediately question a company that offers the same formula for men and women, simply because the hormonal chemistry and biology are so completely different from gender to gender. Typically a product made specifically for men has far superior results to that made for both sexes, or in this case one made for women. In fact, what may be very effective for women, could be useless or even negative for men.

Drug at a Glance

Unlike many sexual enhancement products available today, this one does not claim to be botanical or plant derived. Instead of a long list of high quality ingredients, this formula is said to only contain one pharmaceutical grade element, Sildenafil Citrate.

Drug In Focus

One only needs to do a small amount of research on this active ingredient to find that Sildenafil Citrate is the same active ingredient in the prescription Viagra. Viagra was the first well known male enhancement product to really gain notoriety in the United States. If this product contains the exact same ingredients, we are not sure why a different formula was needed. It seems that the makers of Lovegra may have wanted to get in on the action by creating a new name and marketing ploy, geared toward women. Unfortunately for both products, the Sildenafil Citrate ingredient is loaded with many negative side effects, making its recommendation not likely.

We have found that there are many far better supplements on the market that are created specifically for men and contain all natural ingredients like Tribulus Terrestris, a testosterone booster. Tribulus is often a component in high quality male enhancement supplements, and it works to increase the body’s natural production of the male sex hormone. This increase may lead to a better libido, improved stamina and increased virility. Another core component of a high quality sexual aid is proven aphrodisiacs like Epimedium, which works to increase libido and fight erectile fatigue. Unfortunately for Lovegra, it is lacking both.

Lifestyle

Becoming accustomed to a new supplement may take time. The adjustment stage should not be filled with negative side effects, however. According to the makers of this formula, side effects may include flushing or hot flashes, upset stomach, headaches, dizziness, sensitivity to light, blurred vision. In rare cases even a sudden temporary blindness or deafness may occur.

Along with this laundry list of potential side effects is a list of people who cannot take the product. People with high blood pressure, heart conditions, prostate problems, or liver or kidney problems should not take this product without specific clearance from a doctor. So, if you can take the product the next question is if you would be willing to deal with the potentially horrible side effects.

Positives

• Drug may provide sexual enhancement of some sort

Negatives

• Doesn’t include high quality ingredients like Tribulus Terrestris or Epimedium
• Carries potentially dangerous side effects
• Not safe for everyone
• Marketed to both men and women

Final Thoughts

We know many companies in the supplement business are simply out to make a buck, even at the cost of their customers’ satisfaction. When any company hijacks the formula of another product and re labels it, we question the authenticity of its effectiveness claims. In particular, it is a big red flag that the same formula is marketed to men and women, despite the major differences in sexual biology. Add to this the long list of uncomfortable side effects and exclusions, and one has to wonder if any possible benefits are worth the trade. We believe that when men can find a superior quality product made specifically for them and without all of the side effects, they have truly found something worthwhile. People seeking additional resources about Lovegra, however, are encouraged to look at the sites linked above before deciding whether or not to try this product.

For many years men have been boasting about the effects of Viagra in their sexual behavior, and certainly sales of this product does not appear to be decreasing. But today not only are the products available for men to increase their sexual desire women now have the opportunity to do the same using Female Viagra products such as creams or supplements.

One of the best known of the libido enhancing products that can be seen advertising on the internet today is Vigorelle. This cream acts very quickly and simply must be applied only to the area of the clitoris of a woman just before she is about to have sex.

This product is made using only natural ingredients and does not act as a lubricant. What, in fact, once the cream has not been applied to the clitoral region is that it helps to release the natural juices of the vagina and then increases the size and sensitivity of this part of the body of a woman. Vigorelle has been produced using Western herbalist and methods of traditional Chinese medicine. There are other creams on the market today Vigorelle is one of the few that is made using only natural organic botanical ingredients. This means that do not contain preservatives, perfume or unnatural ingredients that may cause side effects.

These ingredients are composed of a certain formulation in order to help improve the feelings of women during sex. It is not only stimulating sexual response in women, but also increases your excitement, as well as increasing lubrication of the genital area.

The product should be applied directly to the clitoris in order to obtain the maximum effect of a woman in connection with their sexual performance. The effects of this cream are activated through a woman touching. In fact, the best way to achieve the best possible results when using this particular Type of female Viagra is by applying a few drops to the bottom of her clitoris, and then massage the membrane with the use of small circular movements.

So if you are looking for a way to improve your sex life with your partner and help increase your libido then you should seriously consider thinking about using a female Viagra cream such as Vigorelle.

Viagra for Him, Viagra for Her. It sounds like a new ad, doesn’t it? There are two ways Viagra could affect your sex life: if he takes it and if someday she takes it.

If He Takes Viagra
Most people know that Viagra (Sildenafil) is the drug to cure impotency. This can only improve a woman’s sex life right? Not always. Many couples in the age group most affected (the 50s or older) grew up with the idea of the missionary position and thrusting as defining sex. Impotency caused some couples to stop physical intimacy all together. They didn’t know there are other ways to have sex. But, others discovered what the AIDS/Safe Sex Generation takes for granted. More specifically, many of these couples discovered the clitoris. Some of the women had an orgasm for the first time. Viagra may take women backwards. Whatever communication got you to sexual activity in spite of impotency needs to be used again to express your desire to keep doing what you have been doing. If you are someone who stopped everything and aren’t looking forward to going back because it wasn’t that good for you anyway, then you need to find the words to talk about this and learn what you want.

If She Takes Viagra
Viagra works by increasing blood flow to the genital area. The penis and the clitoris are analogous organs. If the penis can become erect through Viagra, why cant the clitoris? An erect clitoris is necessary for female orgasm, as it is for males. So, Viagra could conceivably work for women who are an-orgasmic. There have been a few studies done recently on the use of Viagra in women, but most of them have been performed with too few subjects to make any definite conclusions. The most useful study involved treating 33 post-menopausal women, who complained of sexual dysfunction, with Viagra for a time period of three months. Did treatment improve your sexual function? Mean scores showed that lubrication improved by 23.2%, orgasm by 7.4%, and clitoral sensation by 31.3%. However, overall only 18.1% of the women had a significant therapeutic response. Negative side effects included clitoral discomfort and hypersensitivity in 21% of the women, headache and dizziness. This study shows that overall sexual function did not improve significantly. However, since there have been relatively few studies done on this subject, at this point no definite conclusions can be made regarding the role of Viagra in women.

Precautions
Should any normal human being take Viagra to be better than before? No! In men, the term is priapism, which is a very painful prolonged erection. In women, the analogous problem could be pelvic congestion, which is also painful. Viagra is only for people who are already experiencing difficulty with sex.