Epidemiology of Erectile Dysfunction
ED is a common disorder of male sexual function that affects all age groups and has a profound impact on quality of life. Given the increasing trends in life expectancy across the Western world (i.e., the aging of the general population) and the high prevalence of diabetes and cardiovascular disease, the impact on lifestyle and quality of life imposed by ED in men is projected to be substantial.
– It was estimated that, in 1995, over 152 million men worldwide experienced ED.
– For 2025, the prevalence of ED is predicted to be approximately 322 million worldwide.
The severity, prevalence and incidence of ED increase with age.
The Massachusetts Male Aging Study surveyed 1,709 men aged 40–70 years between 1987 and 1989, using a self-administered questionnaire that asked participants to rate themselves as not having ED, or having minimal ED, moderate ED, or complete ED. There was a total prevalence of erectile dysfunction of 52 percent when participants with minimal (17.2 percent), moderate (25.2 percent) and complete (9.6 percent) dysfunction were combined. Both the prevalence and severity of erectile dysfunction increased proportionally with age. When adjusted for age, patients with lower level of education, heart disease, hypertension, and diabetes had a higher probability of ED.
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– In the same study, a sample of 847 men without ED at baseline (1987– 1989) was followed prospectively until 1995–1997.
The crude incidence rate of ED in this population was estimated to be about 26 cases per 1,000 man-years (95% CI: 22.5–29.9).
The annual age-specific incidence rate of ED increased with each decade of age.
For example, the incidence rates (and 95% CIs) for men in two age groups of 50–59 and 60–69 years were
- 29.8 cases per 1,000 man-years (95% CI: 24.0–37.0)
- 46.4 cases per 1,000 man-years (95% CI: 36.9–58.4), respectively.
In a Canadian cross-sectional survey of primary care facilities, about 50 percent of 3,921 men aged 40–88 years had ED (IIEF “EF” domain score <21). The presence of cardiovascular diseases or diabetes was associated with an increased risk of having ED after adjustment for age and other confounders.